Lambert-eaton myasthenic syndrome

被引：0
作者：
Maria B. Weimer
Joaquin Wong
机构：
[1] Louisiana State University Health Sciences Center,Department of Neurology
来源：
Current Treatment Options in Neurology | 2009年 / 11卷
关键词：
Plasma Exchange; Main Side Effect; Compound Muscle Action Potential; Pyridostigmine; Neuromuscular Transmission;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Lambert Eaton myasthenic syndrome (LEMS) is a rare neuromuscular junction disease. Often, the signs and symptoms of LEMS are mistaken for myasthenia gravis and therefore the workup is misdirected. A physician must look for an occult malignancy when the diagnosis is made and then continue to search for a malignancy for at least 5 years after diagnosis. The diagnosis of LEMS can be confirmed with electrophysiologic studies or with serum calcium channel antibodies. In most patients with LEMS, 3,4-diaminopyridine will improve strength. In patients without malignancy, immunosuppressants do have a role in the treatment of LEMS. Patients and physicians must be aware that certain situations and drugs may exacerbate weakness.
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页码：77 / 84
页数：7
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