Evaluating dopamine transporter imaging as an enrichment biomarker in a phase 2 Parkinson’s disease trial

[1] Hughes AJ(2002)The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service Brain. 125 861-870

[2] Daniel SE(2009)Parkinson's disease is overdiagnosed clinically at baseline in diagnostically uncertain cases: a 3-year European multicenter study with repeat [123I]FP-CIT SPECT Mov Disord 24 500-508

[3] Ben-Shlomo Y(2014)Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study Neurology. 83 406-412

[4] Lees AJ(2016)Accuracy of clinical diagnosis of Parkinson disease: a systematic review and meta-analysis Neurology. 87 237-238

[5] Marshall VL(2007)Role of DAT-SPECT in the diagnostic work up of parkinsonism Mov Disord 22 1229-1238

[6] Reininger CB(2003)Slower progression of Parkinson's disease with ropinirole versus levodopa: the REAL-PET study Ann Neurol 54 93-101

[7] Marquardt M(2002)Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression JAMA. 287 1653-1661

[8] Patterson J(2004)Levodopa and the progression of Parkinson's disease N Engl J Med 351 2498-2508

[9] Hadley DM(2003)Beta-CIT scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA-CIT and CALM-CIT study: long-term imaging assessment Neurology. 60 A293-1797

[10] Oertel WH(2014)Longitudinal follow-up of SWEDD subjects in the PRECEPT study Neurology. 82 1791-S62

[1] Hughes AJ(2002)The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service Brain. 125 861-870

[2] Daniel SE(2009)Parkinson's disease is overdiagnosed clinically at baseline in diagnostically uncertain cases: a 3-year European multicenter study with repeat [123I]FP-CIT SPECT Mov Disord 24 500-508

[3] Ben-Shlomo Y(2014)Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study Neurology. 83 406-412

[4] Lees AJ(2016)Accuracy of clinical diagnosis of Parkinson disease: a systematic review and meta-analysis Neurology. 87 237-238

[5] Marshall VL(2007)Role of DAT-SPECT in the diagnostic work up of parkinsonism Mov Disord 22 1229-1238

[6] Reininger CB(2003)Slower progression of Parkinson's disease with ropinirole versus levodopa: the REAL-PET study Ann Neurol 54 93-101

[7] Marquardt M(2002)Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression JAMA. 287 1653-1661

[8] Patterson J(2004)Levodopa and the progression of Parkinson's disease N Engl J Med 351 2498-2508

[9] Hadley DM(2003)Beta-CIT scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA-CIT and CALM-CIT study: long-term imaging assessment Neurology. 60 A293-1797

[10] Oertel WH(2014)Longitudinal follow-up of SWEDD subjects in the PRECEPT study Neurology. 82 1791-S62