TFE3 fusions escape from controlling of mTOR signaling pathway and accumulate in the nucleus promoting genes expression in Xp11.2 translocation renal cell carcinomas

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作者
Xiaoqin Yin
Bo Wang
Weidong Gan
Wenyuan Zhuang
Zou Xiang
Xiaodong Han
Dongmei Li
机构
[1] Nanjing University,Immunology and Reproduction Biology Laboratory & State Key Laboratory of Analytical Chemistry for Life Science, Medical School
[2] Nanjing University,Jiangsu Key Laboratory of Molecular Medicine
[3] Affiliated Drum Tower Hospital of Medical School of Nanjing University,Department of Urology
[4] The Hong Kong Polytechnic University,Department of Health Technology and Informatics, Faculty of Health and Social Sciences
来源
Journal of Experimental & Clinical Cancer Research | / 38卷
关键词
TFE3; mTOR; Subcellular localization; Nuclear retention; Lysosome; Transcription factor;
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