Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells

[51] Patel NS(2014)Targeting nrf2 signaling to combat chemoresistance J Cancer Prev 19 111-164

[52] Beaulieu-Abdelahad D(2010)Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation Neurobiol Dis 37 118-832

[53] Bachmeier C(2008)Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells Cell Res 18 879-2060

[54] Canne IG(2017)Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma Free Radic Biol Med 106 24-undefined

[55] Merrick KA(2012)Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis Autophagy. 8 559-undefined

[56] Morandell S(2003)Tumor necrosis factor signaling Cell Death Differ 10 45-undefined

[57] Zhu CQ(2010)Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L Cancer Lett 297 155-undefined

[58] Braun CJ(2017)A pan-Cancer Proteogenomic atlas of PI3K/AKT/mTOR pathway alterations Cancer Cell 31 820-undefined

[59] Grant RA(2018)3′-epi-12beta-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells Theranostics. 8 2044-undefined

[60] Peng CY(undefined)undefined undefined undefined undefined-undefined

[51] Patel NS(2014)Targeting nrf2 signaling to combat chemoresistance J Cancer Prev 19 111-164

[52] Beaulieu-Abdelahad D(2010)Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation Neurobiol Dis 37 118-832

[53] Bachmeier C(2008)Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells Cell Res 18 879-2060

[54] Canne IG(2017)Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma Free Radic Biol Med 106 24-undefined

[55] Merrick KA(2012)Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis Autophagy. 8 559-undefined

[56] Morandell S(2003)Tumor necrosis factor signaling Cell Death Differ 10 45-undefined

[57] Zhu CQ(2010)Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L Cancer Lett 297 155-undefined

[58] Braun CJ(2017)A pan-Cancer Proteogenomic atlas of PI3K/AKT/mTOR pathway alterations Cancer Cell 31 820-undefined

[59] Grant RA(2018)3′-epi-12beta-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells Theranostics. 8 2044-undefined

[60] Peng CY(undefined)undefined undefined undefined undefined-undefined