Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells

[21] Liu X(2017)Kupffer cell-derived Tnf triggers Cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS Cancer Cell 31 771-6324

[22] Corson TW(2011)Regulation of autophagy by ROS: physiology and pathology Trends Biochem Sci 36 30-1774

[23] Crews CM(2007)Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells Cancer Res 67 6314-261

[24] Liu Z(2013)Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK EMBO Mol Med 5 1759-189

[25] Ma L(2016)The synthetic beta-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway Cancer Lett 371 251-721

[26] Wen ZS(2014)Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway Cancer Lett 343 179-854

[27] Hu Z(2014)Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel? Nat Rev Cancer 14 709-312

[28] Wu FQ(2010)ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy Autophagy. 6 838-105

[29] Li W(2017)Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-beta 1-dependent activation of Smad/ERK signaling Cell Death Dis 8 248-100

[30] Uttarkar S(2013)Targeting apoptosis pathways in cancer by Chinese medicine Cancer Lett 332 304-451

[21] Liu X(2017)Kupffer cell-derived Tnf triggers Cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS Cancer Cell 31 771-6324

[22] Corson TW(2011)Regulation of autophagy by ROS: physiology and pathology Trends Biochem Sci 36 30-1774

[23] Crews CM(2007)Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells Cancer Res 67 6314-261

[24] Liu Z(2013)Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK EMBO Mol Med 5 1759-189

[25] Ma L(2016)The synthetic beta-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway Cancer Lett 371 251-721

[26] Wen ZS(2014)Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway Cancer Lett 343 179-854

[27] Hu Z(2014)Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel? Nat Rev Cancer 14 709-312

[28] Wu FQ(2010)ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy Autophagy. 6 838-105

[29] Li W(2017)Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-beta 1-dependent activation of Smad/ERK signaling Cell Death Dis 8 248-100

[30] Uttarkar S(2013)Targeting apoptosis pathways in cancer by Chinese medicine Cancer Lett 332 304-451