Preclinical Imaging Evaluation of Novel TSPO-PET Ligand 2-(5,7-Diethyl-2-(4-(2-[18F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([18F]VUIIS1008) in Glioma

被引：0
|
作者：
Dewei Tang
Michael L. Nickels
M. Noor Tantawy
Jason R. Buck
H. Charles Manning
机构：
[1] Vanderbilt University Medical Center,Vanderbilt University Institute of Imaging Science (VUIIS)
[2] Vanderbilt University Medical Center,Department of Radiology and Radiological Sciences
[3] Vanderbilt University Medical Center,Program in Chemical and Physical Biology
[4] Vanderbilt University Medical Center,Vanderbilt
[5] Vanderbilt University,Ingram Cancer Center
[6] Vanderbilt University Medical Center,Department of Biomedical Engineering
[7] Vanderbilt University Medical Center,Department of Neurosurgery
来源：
Molecular Imaging and Biology | 2014年 / 16卷
关键词：
PET; DPA-714; VUIIS1008; TSPO; Glioma; Cancer imaging;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：813 / 820
页数：7
相关论文
共 26 条
  • [21] Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[18F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer
    Cheung, Yiu-Yin
    Nickels, Michael L.
    Tang, Dewei
    Buck, Jason R.
    Manning, H. Charles
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (18) : 4466 - 4471
  • [22] Synthesis and evaluation of 5,7-dihydro-3-[2-[1-(4-[18F] fluorobenzyl)-4-piperidinyl]ethyl]-6H-pyrrolo[3,2-f]1,2-benzisoxazol-6-one for in vivo mapping of acetylcholinesterase
    Lee, SY
    Choe, YS
    Kim, YR
    Paik, JY
    Choi, BW
    Kim, SE
    Lee, KH
    Choi, Y
    Kim, BT
    NUCLEAR MEDICINE COMMUNICATIONS, 2004, 25 (06) : 591 - 596
  • [23] Click Synthesis and Biologic Evaluation of (R)- and (S)-2-Amino-3-[1-(2-[18F]Fluoroethyl)-1H-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography
    McConathy, Jonathan
    Zhou, Dong
    Shockley, Stephany E.
    Jones, Lynne A.
    Griffin, Elizabeth A.
    Lee, Hsiaoju
    Adams, Susan J.
    Mach, Robert H.
    MOLECULAR IMAGING, 2010, 9 (06) : 329 - 342
  • [24] Radiosynthesis of 3-(3-[18F]fluoropropoxy)-4-(benzyloxy)-N-[(1-dimethylaminocyclopentyl)methyl]-5-methoxybenzamide, a potential PET radiotracer for the glycine transporter GlyT-2
    Tian, Halbin
    Vogel, Rebecca
    Amici, Louis
    Tamagnan, Gilles
    Baldwin, Ronald M.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2006, 49 (14) : 1247 - 1258
  • [25] Synthesis and evaluation of 6-[1-(2-[18F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain
    Fujinaga, Masayuki
    Yamasaki, Tomoteru
    Kawamura, Kazunori
    Kumata, Katsushi
    Hatori, Akiko
    Yui, Joji
    Yanamoto, Kazuhiko
    Yoshida, Yuichiro
    Ogawa, Masanao
    Nengaki, Nobuki
    Maeda, Jun
    Fukumura, Toshimitsu
    Zhang, Ming-Rong
    BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (01) : 102 - 110
  • [26] Synthesis and in vitro characterization of trans- and cis-[18F]-4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]-3-fluoropiperidine-1-carboxylates as new potential PET radiotracer candidates for the NR2B subtype N-methyl-D-aspartate receptor
    Koudih, Radouane
    Gilbert, Gwenaelle
    Dhilly, Martine
    Abbas, Ahmed
    Barre, Louisa
    Debruyne, Daniele
    Sobrio, Franck
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 53 : 408 - 415
123