Integrative genomics analysis of various omics data and networks identify risk genes and variants vulnerable to childhood-onset asthma

被引:0
作者
Xiuqing Ma
Peilan Wang
Guobing Xu
Fang Yu
Yunlong Ma
机构
[1] Chinese PLA General Hospital,Department of Pulmonary & Critical Care Medicine
[2] Chinese PLA General Hospital,Outpatient Department
[3] Zhongxiang People’s Hospital,Department of Cardiovascular Medicine
[4] Chinese PLA General Hospital,Department of Pediatrics
[5] Wenzhou Medical University,Institute of Biomedical Big Data, School of Biomedical Engineering, School of Ophthalmology & Optometry and Eye Hospital
[6] Zhejiang University School of Medicine,State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases
来源
BMC Medical Genomics | / 13卷
关键词
Genetic variants; GWAS; Risk genes; Gene expression; Asthma;
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[41]  
Demenais F(2008)DrugBank: a knowledgebase for drugs, drug actions and drug targets Nucleic Acids Res 36 bav028-213
[42]  
Strachan DP(2012)GLAD4U: deriving and prioritizing gene lists from PubMed literature BMC Genomics 13 886-1349
[43]  
Bouzigon E(2015)DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes Database 2015 W214-30
[44]  
Heath S(2016)An integrative genomic study implicates the postsynaptic density in the pathogenesis of bipolar disorder Neuropsychopharmacology 41 1845-381
[45]  
von Mutius E(2010)The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function Nucleic Acids Res 38 62-594
[46]  
Farrall M(2019)Upper airway cell Transcriptomics identify a major new immunological phenotype with strong clinical correlates in young children with acute wheezing J Immunol 202 522-39
[47]  
Lathrop M(2019)Mechanistic interpretation of non-coding variants for discovering transcriptional regulators of drug response BMC Biol 17 1095-386
[48]  
Cookson W(2017)A genetic variant associated with five vascular diseases is a distal regulator of Endothelin-1 gene expression Cell 170 204-669
[49]  
Ullemar V(2012)Interpreting noncoding genetic variation in complex traits and human disease Nat Biotechnol 30 1346-295
[50]  
Magnusson PK(2013)Human disease-associated genetic variation impacts large intergenic non-coding RNA expression PLoS Genet 9 24-717