Model verification tools: a computational framework for verification assessment of mechanistic agent-based models

被引:0
作者
Giulia Russo
Giuseppe Alessandro Parasiliti Palumbo
Marzio Pennisi
Francesco Pappalardo
机构
[1] University of Catania,Department of Drug and Health Sciences
[2] University of Catania,Department of Mathematics and Computer Science
[3] University of Eastern Piedmont,Computer Science Institute, DiSIT
来源
BMC Bioinformatics | / 22卷
关键词
Agent-based models; Verification assessment; In silico trials; Medicinal product; Regulatory context; COVID-19;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 69 条
[1]  
Viceconti M(2017)In silico assessment of biomedical products: the conundrum of rare but not so rare events in two case studies Proc Inst Mech Eng H 231 455-466
[2]  
Cobelli C(2019)In silico clinical trials: concepts and early adoptions Brief Bioinform 20 1699-1708
[3]  
Haddad T(1980)Establishing the credibility of simulations SIMULATION 34 101-105
[4]  
Himes A(2017)A framework to establish credibility of computational models in biology Prog Biophys Mol Biol 129 13-19
[5]  
Kovatchev B(2016)Promoting adoption of the 3Rs through regulatory qualification ILAR J 57 221-225
[6]  
Palmer M(2016)Uncertainty and variability in computational and mathematical models of cardiac physiology J Physiol 594 6833-6847
[7]  
Pappalardo F(2017)In silico adjuvant design and validation Methods Mol Biol 1494 107-125
[8]  
Russo G(2020)Credibility of in silico trial technologies—a theoretical framing IEEE J Biomed Heal Inf 24 4-13
[9]  
Tshinanu FM(2015)Agent based modeling of the effects of potential treatments over the blood–brain barrier in multiple sclerosis J Immunol Methods 427 6-12
[10]  
Viceconti M(2017)Combining agent based-models and virtual screening techniques to predict the best citrus-derived vaccine adjuvants against human papilloma virus BMC Bioinf 18 544-16