Pharmacokinetics and pharmacodynamics of the novel PAR-1 antagonist vorapaxar in patients with end-stage renal disease

被引:0
作者
Teddy Kosoglou
Walter K. Kraft
Bharath Kumar
Paul Statkevich
Fengjuan Xuan
Lei Ma
Lisa K. Jennings
James E. Schiller
Ronald B. Langdon
David L. Cutler
机构
[1] Merck Sharp & Dohme Corp.,Department of Pharmacology and Experimental Therapeutics
[2] Thomas Jefferson University,Clinical Pharmacology, Merck Research Laboratories
[3] University of Tennessee Health Science Center,undefined
[4] Merck Sharp & Dohme Corp.,undefined
来源
European Journal of Clinical Pharmacology | 2012年 / 68卷
关键词
Vorapaxar; SCH 530348; PAR-1; Renal disease; Pharmacokinetics; Pharmacodynamics;
D O I
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中图分类号
学科分类号
摘要
引用
收藏
页码:1049 / 1056
页数:7
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