Synthesis of temperature-sensitive micron-sized monodispersed composite polymer particles and its application as a carrier for biomolecules

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作者
M. Okubo
H. Ahmad
T. Suzuki
机构
[1] Department of Chemical Science and Engineering Faculty of Engineering Kobe University Rokko,
[2] Nada,undefined
[3] Kobe 657-8501 Japan,undefined
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Key words Composite particle; temperature-sensitive; biomolecules; specific activity; adsorption;
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摘要
 Temperature-sensitive micron-sized monodispersed composite polymer particles were prepared by seeded copolymerization of dimethylaminoethyl methacrylate and ethylene glycol dimethacrylate with 1.77 μm-sized monodispersed polystyrene seed particles. The change in surface property at temperature above and below 35 °C was examined by differential scanning calorimetry, trypsin activity and the adsorption/ desorption behaviors of low molecular weight cationic emulsifier as well as biomolecules.
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页码:470 / 475
页数:5
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