Small-molecule WNK inhibition regulates cardiovascular and renal function

被引:0
|
作者
Ken Yamada
Hyi-Man Park
Dean F Rigel
Keith DiPetrillo
Erin J Whalen
Anthony Anisowicz
Michael Beil
James Berstler
Cara Emily Brocklehurst
Debra A Burdick
Shari L Caplan
Michael P Capparelli
Guanjing Chen
Wei Chen
Bethany Dale
Lin Deng
Fumin Fu
Norio Hamamatsu
Kouki Harasaki
Tracey Herr
Peter Hoffmann
Qi-Ying Hu
Waan-Jeng Huang
Neeraja Idamakanti
Hidetomo Imase
Yuki Iwaki
Monish Jain
Jey Jeyaseelan
Mitsunori Kato
Virendar K Kaushik
Darcy Kohls
Vidya Kunjathoor
Daniel LaSala
Jongchan Lee
Jing Liu
Yang Luo
Fupeng Ma
Ruowei Mo
Sarah Mowbray
Muneto Mogi
Flavio Ossola
Pramod Pandey
Sejal J Patel
Swetha Raghavan
Bahaa Salem
Yuka H Shanado
Gary M Trakshel
Gordon Turner
Hiromichi Wakai
Chunhua Wang
机构
[1] Novartis Institutes for BioMedical Research,
来源
Nature Chemical Biology | 2016年 / 12卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
A selective inhibitor of the With-No-Lysine (K) (WNK) kinase family reduces blood pressure and increases electrolyte excretion in hypertensive rats.[graphic not available: see fulltext]
引用
收藏
页码:896 / 898
页数:2
相关论文
共 50 条
  • [41] Small-molecule mimetics
    Murcko, M
    DRUG DISCOVERY TODAY, 1996, 1 (10) : 408 - 410
  • [42] Small-molecule control of protein function through Staudinger reduction
    Ji Luo
    Qingyang Liu
    Kunihiko Morihiro
    Alexander Deiters
    Nature Chemistry, 2016, 8 : 1027 - 1034
  • [43] Discovery of a small-molecule probe for V-ATPase function
    Schreiber, Stuart L. (stuart_schreiber@harvard.edu), 1600, American Chemical Society (137):
  • [44] Discovery of a Small-Molecule Probe for V-ATPase Function
    Adrich, Leslie N.
    Kuo, Szu-Yu
    Castoreno, Adam B.
    Goel, Gautam
    Kuballa, Petric
    Rees, Matthew G.
    Seashore-Ludlow, Brinton A.
    Cheah, Jaime H.
    Latorre, Isabel J.
    Schreiber, Stuart L.
    Shamji, Alykhan F.
    Xavier, Ramnik J.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (16) : 5563 - 5568
  • [45] Small-molecule inhibitors of microRNA miR-21 function
    Gumireddy, Kiranmai
    Young, Douglas D.
    Xiong, Xin
    Hogenesch, John B.
    Huang, Qihong
    Deiters, Alexander
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (39) : 7482 - 7484
  • [46] Small-molecule control of protein function through Staudinger reduction
    Luo, Ji
    Liu, Qingyang
    Morihiro, Kunihiko
    Deiters, Alexander
    NATURE CHEMISTRY, 2016, 8 (11) : 1027 - 1034
  • [47] Inhibition of cancer cell viability and selective inhibition of lysyl oxidase with small-molecule Inhibitors
    Johnston, Kathryn
    Lopez, Karlo
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [48] Small-molecule inhibition of the archetypal UbiB protein COQ8
    Nathan H. Murray
    Christopher R. M. Asquith
    Zixiang Fang
    Michael P. East
    Naomi Ptak
    Robert W. Smith
    James D. Vasta
    Chad A. Zimprich
    Cesear R. Corona
    Matthew B. Robers
    Gary L. Johnson
    Craig A. Bingman
    David J. Pagliarini
    Nature Chemical Biology, 2023, 19 : 230 - 238
  • [49] Small-Molecule Gankyrin Inhibition as a Therapeutic Strategy for Breast and Lung Cancer
    Kanabar, Dipti
    Goyal, Mimansa
    Kane, Emma, I
    Chavan, Tejashri
    Kabir, Abbas
    Wang, Xuechun
    Shukla, Snehal
    Almasri, Joseph
    Goswami, Sona
    Osman, Gizem
    Kokolis, Marino
    Spratt, Donald E.
    Gupta, Vivek
    Muth, Aaron
    JOURNAL OF MEDICINAL CHEMISTRY, 2022, : 8975 - 8997
  • [50] Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
    Ferreras, JA
    Ryu, JS
    Di Lello, F
    Tan, DS
    Quadri, LEN
    NATURE CHEMICAL BIOLOGY, 2005, 1 (01) : 29 - 32