This Review analyzes the changing face of acute kidney injury in children in terms of etiology, incidence, diagnosis, treatment and long-term outcomes. The evidence base for conservative management of pediatric acute kidney injury (with agents such as diuretics, nesiritide and fenoldopam) is assessed, and the author offers advice on the optimal timing and modality of renal replacement therapy.
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Univ Cattolica Sacro Cuore, Policlin Univ A Gemelli, I-00168 Rome, ItalySan Bortolo Hosp, Int Renal Res Inst IRRIV, Dept Nephrol Dialysis & Transplantat, I-36100 Vicenza, Italy
Antonelli, Massimo
Payen, Didier
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Univ Paris 07, Lariboisiere Hosp, AP HP, Dept Anesthesiol & Crit Care, F-75475 Paris 10, FranceSan Bortolo Hosp, Int Renal Res Inst IRRIV, Dept Nephrol Dialysis & Transplantat, I-36100 Vicenza, Italy
Payen, Didier
Prowle, John R.
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Royal London Hosp, Adult Crit Care Unit, Barts Hlth, London E1 1BB, EnglandSan Bortolo Hosp, Int Renal Res Inst IRRIV, Dept Nephrol Dialysis & Transplantat, I-36100 Vicenza, Italy
Prowle, John R.
Vincent, Jean-Louis
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Univ Libre Bruxelles, Erasme Hosp, Dept Intens Care, B-1070 Brussels, BelgiumSan Bortolo Hosp, Int Renal Res Inst IRRIV, Dept Nephrol Dialysis & Transplantat, I-36100 Vicenza, Italy