Population pharmacokinetic modelling of imatinib in healthy subjects receiving a single dose of 400 mg

被引：0
|
作者：
Yi-Han Chien
Gudrun Würthwein
Pablo Zubiaur
Bianca Posocco
María Ángeles Pena
Alberto M. Borobia
Sara Gagno
Francisco Abad-Santos
Georg Hempel
机构：
[1] Westfälische Wilhelms-Universität Münster,Clinical Pharmacology Department
[2] Institut für Pharmazeutische und Medizinische Chemie-Klinische Pharmazie,Experimental and Clinical Pharmacology Unit
[3] Hospital Universitario de la Princesa,Farmacología Clínica
[4] Pharmacology Department,Clinical Pharmacology Department
[5] Faculty of Medicine,undefined
[6] Universidad Autonoma de Madrid,undefined
[7] Instituto de Investigación Sanitaria la Princesa (IIS-Princesa),undefined
[8] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD),undefined
[9] Centro di Riferimento Oncologico di Aviano (CRO),undefined
[10] IRCCS,undefined
[11] Hospital Universitario Marqués de Valdecilla-Pabellón,undefined
[12] Hospital Universitario La Paz,undefined
[13] Pharmacology Department,undefined
[14] Faculty of Medicine,undefined
[15] Universidad Autonoma de Madrid,undefined
[16] IdiPAZ,undefined
来源：
Cancer Chemotherapy and Pharmacology | 2022年 / 90卷
关键词：
Imatinib; Population pharmacokinetics; NONMEM; Ph + leukemia; Empirical Bayesian estimation; MAP Bayesian estimation;
D O I：
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学科分类号：
摘要：
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页码：125 / 136
页数：11
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