Comparing the Fatty Acid Composition and Neuroprotective Effects of Some Lamiaceae Taxa from Turkey

被引：0
作者：
Tugce Fafal
Gizem Kaftan
Pelin Tastan
Bijen Kivcak
Guliz Armagan
机构：
[1] Ege University,
[2] Faculty of Pharmacy,undefined
[3] Pharmacognosy Department,undefined
[4] Ege University,undefined
[5] Faculty of Pharmacy,undefined
[6] Biochemistry Department,undefined
来源：
Chemistry of Natural Compounds | 2022年 / 58卷
关键词：
neuroprotection; fatty acids;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study aims to analyze the fatty acid composition and neuroprotective potential of some selected Lamiaceae taxa from Turkey. For this purpose, methanol extracts of Lamium album L., Lamium garganicum L., Phlomis rigida Labill., Salvia syriaca L., Salvia sclarea L., and Stachys cretica subsp. anatolica Rech. f. were investigated for their activity against hydrogen peroxide induced neuronal cell death. The fatty acid compositions were analyzed by GC-FID, and the IA and IT indices and the ω3/ω6 ratio were also calculated. Saturated and unsaturated fatty acids of selected Lamiaceae species were measured to range from 8.92–17.59% and 75.13–84.57%, respectively. Phlomis rigida with the highest ω3/ω6 was shown to have the highest neuroprotection against H2O2-induced cell toxicity.
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页码：208 / 212
页数：4
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