The frequencies of CYP2D6 alleles and their impact on clinical outcomes of adjuvant tamoxifen therapy in Syrian breast cancer patients

被引:0
作者
Wouroud Ismail Al-khalil
Lana Al-Salhi
Sara Rijjal
Majd Aljamali
Lama A. Youssef
机构
[1] Damascus University,Department of Pharmaceutics and Pharmaceutical Technology, Program of Clinical and Hospital Pharmacy, Faculty of Pharmacy
[2] Damascus University,Department of Biochemistry and Microbiology, Faculty of Pharmacy
[3] International University for Science and Technology (IUST),Faculty of Pharmacy
[4] National Commission for Biotechnology (NCBT),undefined
来源
BMC Cancer | / 22卷
关键词
Breast cancer; Tamoxifen; Genotyping; Syria;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 149 条
  • [1] Sung H(2021)Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 71 209-249
  • [2] Ferlay J(2020)Molecular classification of breast cancer Adv Anat Pathol 27 27-35
  • [3] Siegel RL(2011)Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials Lancet. 378 771-84
  • [4] Laversanne M(2019)Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen Expert Rev Clin Pharmacol 12 523-536
  • [5] Soerjomataram I(2013)PharmGKB summary: tamoxifen pathway, pharmacokinetics Pharmacogenet Genomics 23 643-647
  • [6] Jemal A(2020)Standardizing CYP2D6 genotype to phenotype translation: consensus recommendations from the clinical pharmacogenetics implementation consortium and Dutch pharmacogenetics working group Clin Transl Sci 13 116-124
  • [7] Tsang JYS(2017)Improved prediction of endoxifen metabolism by CYP2D6 genotype in breast cancer patients treated with tamoxifen Front Pharmacol 8 582-1429
  • [8] Tse GM(2021)Clinical CYP2D6 genotyping to personalize adjuvant tamoxifen treatment in ER-positive breast cancer patients: current status of a controversy Cancers (Basel) 13 771-557
  • [9] Davies C(2022)Frequencies of CYP2D6 genetic polymorphisms in Arab populations Hum Genomics 16 6-31
  • [10] Godwin J(2008)Association between CYP2D6*10 genotype and survival of breast cancer patients receiving tamoxifen treatment Ann Oncol 19 1423-879