Simultaneous detection of epinephrine, uric acid, and ascorbic acid with graphene-modified electrode

A graphene-modified glassy carbon electrode was obtained via drop-casting method and applied to the simultaneous detection of epinephrine, uric acid, and ascorbic acid by cyclic voltammetry in a phosphate buffer solution (pH 3.0). The oxidation potentials of epinephrine, uric acid, and ascorbic acid were 0.484, 0.650, and 0.184 V at the graphene-modified glassy carbon electrode, respectively. The peak separation between epinephrine Pand uric acid, epinephrine and ascorbic acid, and uric acid and ascorbic acid was about 166, 300, and 466 mV, respectively. So, this graphene-modified electrode can be used for simultaneous determination of each component in a mixture.