Weight Loss in Patients with Dementia: Considering the Potential Impact of Pharmacotherapy

被引：0

作者：

Bart A. A. Franx

Ilse A. C. Arnoldussen

Amanda J. Kiliaan

Deborah R. Gustafson

机构：

[1] Radboud University Medical Center,Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour

[2] State University of New York,Department of Neurology, Section for NeuroEpidemiology

[3] Downstate Medical Center,Neuropsychiatric Epidemiology Unit (EPINEP), Institute for Neuroscience and Physiology

[4] Sahlgrenska Academy at the University of Gothenburg,Department of Health and Education

[5] University of Skövde,undefined

来源：

Drugs & Aging | 2017年 / 34卷

关键词：

Dementia; Mild Cognitive Impairment; Memantine; Mirtazapine; Body Weight Loss;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Unintentional body weight loss is common in patients with dementia and is linked to cognitive impairment and poorer disease outcomes. It is proposed that some dementia medications with market approval, while aiming to improve cognitive and functional outcomes of a patient with dementia, are associated with reported body weight or body mass index loss. This review presents evidence in the published literature on body weight loss in dementia, describes selected theories behind body weight loss, evaluates the potential impact of approved dementia pharmacotherapies on body weight, considers the potential role for medical foods, understands the potential influence of treatments for neuropsychiatric symptoms and signs, and finally, summarizes this important area.

引用

页码：425 / 436

页数：11

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