Chaperoning cell death: a critical dual role for Hsp90 in small-cell lung cancer

被引：0
|
作者：
Paul Workman
Marissa V Powers
机构：
[1] Paul Workman and Marissa V. Powers are in the Cancer Research UK Centre for Cancer Therapeutics,
[2] The Institute of Cancer Research,undefined
[3] Haddow Laboratories,undefined
[4] 15 Cotswold Road,undefined
[5] Sutton,undefined
[6] Surrey SM2 5NG,undefined
[7] UK. paul.workman@icr.ac.uk,undefined
来源：
Nature Chemical Biology | 2007年 / 3卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Chemical probes reveal Hsp90 to be a key molecule for the control of apoptosis in small-cell lung cancer—with important implications for Hsp90 biology and cancer treatment.
引用
收藏
页码：455 / 457
页数：2
相关论文
共 50 条
  • [31] The role of extracellular matrix in small-cell lung cancer
    Rintoul, Robert C.
    Sethi, Tariq
    LANCET ONCOLOGY, 2001, 2 (07): : 437 - 442
  • [32] The Role of Radiotherapy in the Treatment of Small-Cell Lung Cancer
    Nosaki, Kaname
    Seto, Takashi
    CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2015, 16 (12)
  • [33] The role of carboplatin in the treatment of small-cell lung cancer
    Ettinger, DS
    ONCOLOGY-NEW YORK, 1998, 12 (01): : 36 - 43
  • [34] The role of cisplatin in the treatment of small-cell lung cancer?
    Berghmans, T
    Paesmans, M
    Sculier, JP
    ANNALS OF ONCOLOGY, 2001, 12 (05) : 585 - 586
  • [35] Hsp90 phosphorylation is linked to its chaperoning function - Assembly of the reovirus cell attachment protein
    Zhao, YG
    Gilmore, R
    Leone, G
    Coffey, MC
    Weber, B
    Lee, PWK
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (35) : 32822 - 32827
  • [36] Targeting KRAS-Mutant Non-Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib
    Acquaviva, Jaime
    Smith, Donald L.
    Sang, Jim
    Friedland, Julie C.
    He, Suqin
    Sequeira, Manuel
    Zhang, Chaohua
    Wada, Yumiko
    Proia, David A.
    MOLECULAR CANCER THERAPEUTICS, 2012, 11 (12) : 2633 - 2643
  • [37] Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models
    David A. Proia
    Jim Sang
    Suqin He
    Donald L. Smith
    Manuel Sequeira
    Chaohua Zhang
    Yuan Liu
    Shuxia Ye
    Dan Zhou
    Ronald K. Blackman
    Kevin P. Foley
    Keizo Koya
    Yumiko Wada
    Investigational New Drugs, 2012, 30 : 2201 - 2209
  • [38] Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models
    Proia, David A.
    Sang, Jim
    He, Suqin
    Smith, Donald L.
    Sequeira, Manuel
    Zhang, Chaohua
    Liu, Yuan
    Ye, Shuxia
    Zhou, Dan
    Blackman, Ronald K.
    Foley, Kevin P.
    Koya, Keizo
    Wada, Yumiko
    INVESTIGATIONAL NEW DRUGS, 2012, 30 (06) : 2201 - 2209
  • [39] Prognostic value of the mRNA expression of members of the HSP90 family in non-small cell lung cancer
    Liu, Kang
    Kang, Min
    Li, Jixi
    Qin, Wen
    Wang, Rensheng
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 17 (04) : 2657 - 2665
  • [40] Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis
    Bellaye, Pierre-Simon
    Shimbori, Chiko
    Yanagihara, Toyoshi
    Carlson, David A.
    Hughes, Philip
    Upagupta, Chandak
    Sato, Seidai
    Wheildon, Nolan
    Haystead, Timothy
    Ask, Kjetil
    Kolb, Martin
    EUROPEAN RESPIRATORY JOURNAL, 2018, 51 (02)
12345