Belimumab: A Guide to Its Use in Systemic Lupus Erythematosus

被引：0

作者：

Lesley J. Scott

Celeste B. Burness

Paul L. McCormack

机构：

[1] Adis,

来源：

BioDrugs | 2012年 / 26卷

关键词：

Systemic Lupus Erythematosus; Placebo Recipient; Infusion Reaction; Physical Component Summary Score; Belimumab;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Belimumab (Benlysta ®), a fully human recombinant IgG1λ monoclonal antibody that inhibits the binding of soluble B lymphocyte stimulator to B cells, is indicated for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity despite receiving standard therapy. In multinational trials, significantly more belimumab recipients than placebo recipients achieved an SLE Responder Index response at 52 weeks.

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页码：195 / 199

页数：4

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