Belimumab: A Guide to Its Use in Systemic Lupus Erythematosus

被引:0
作者
Lesley J. Scott
Celeste B. Burness
Paul L. McCormack
机构
[1] Adis,
来源
BioDrugs | 2012年 / 26卷
关键词
Systemic Lupus Erythematosus; Placebo Recipient; Infusion Reaction; Physical Component Summary Score; Belimumab;
D O I
暂无
中图分类号
学科分类号
摘要
Belimumab (Benlysta ®), a fully human recombinant IgG1λ monoclonal antibody that inhibits the binding of soluble B lymphocyte stimulator to B cells, is indicated for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity despite receiving standard therapy. In multinational trials, significantly more belimumab recipients than placebo recipients achieved an SLE Responder Index response at 52 weeks.
引用
收藏
页码:195 / 199
页数:4
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