Belimumab: A Guide to Its Use in Systemic Lupus Erythematosus

被引：0
作者：
Lesley J. Scott
Celeste B. Burness
Paul L. McCormack
机构：
[1] Adis,
来源：
BioDrugs | 2012年 / 26卷
关键词：
Systemic Lupus Erythematosus; Placebo Recipient; Infusion Reaction; Physical Component Summary Score; Belimumab;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Belimumab (Benlysta ®), a fully human recombinant IgG1λ monoclonal antibody that inhibits the binding of soluble B lymphocyte stimulator to B cells, is indicated for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity despite receiving standard therapy. In multinational trials, significantly more belimumab recipients than placebo recipients achieved an SLE Responder Index response at 52 weeks.
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页码：195 / 199
页数：4
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