Synthesis of thieno[3,4-d]pyrimidines by the reactions of 3-amino-4-carbamoylthiophene derivatives with 1,3-dicarbonyl compounds

被引：0
作者：
S. A. Ryndina
A. V. Kadushkin
N. P. Solov"eva
V. G. Granik
机构：
[1] State Scientific Center of the Russian Federation “Organic Intermediate Products and Dyes Institute”,Center of Drug Chemistry
[2] All-Russian Research Chemical Pharmaceutical Institute,undefined
来源：
Russian Chemical Bulletin | 2002年 / 51卷
关键词：
thiophenes; thieno[3,4-; ]pyrimidines; 1,3-dicarbonyl compounds; cyclization; alkylation;
D O I：
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学科分类号：
摘要：
The reactions of ethyl 3-amino-4-carbamoyl-5-methylthiophene-2-carboxylate with 1,3-dicarbonyl compounds were studied. During the reactions, the corresponding ketone is eliminated to give ethyl 5-methyl-4-oxo-3,4-dihydrothieno[3,4-d]pyrimidine-7-carboxylates.
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页码：1879 / 1885
页数：6
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