Effect of wheat germ on metabolic markers: a systematic review and meta-analysis of randomized controlled trials

被引：0
作者：
Humna Liaqat
Eunseon Jeong
Kyeong Jin Kim
Ji Yeon Kim
机构：
[1] Seoul National University of Science and Technology,Department of Food Science and Technology
[2] Seoul National University of Science and Technology,Department of Nano Bio Engineering
来源：
Food Science and Biotechnology | 2020年 / 29卷
关键词：
Wheat germ; Metabolic markers; Cholesterol; Triglycerides; Glucose;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This systematic review and meta-analysis aim to evaluate the association of wheat germ interventions and metabolic markers. An electronic search was performed by mid-May 2019 in the PubMed, Google Scholar, and Web of Science databases. Quality was evaluated using the risk of bias assessment tools. Thirty-three randomized controlled trials (RCTs) were identified, among which ten were suitable and systematically reviewed based on biomarkers (cholesterol, triglycerides, glucose, and oxidative stress). Three biomarkers in five eligible studies were investigated by meta-analysis. Total cholesterol showed non-significant results (p = 0.98), with standard mean difference (SMD) of − 0.01 (95% confidence interval; − 0.17, 0.16). The SMD was − 0.06 (95% CI − 0.41, 0.29, n = 4) for triglycerides and − 0.09 (95% CI − 0.62, 0.45, n = 2) for glucose. No biomarkers showed heterogeneity (0%). This review revealed non-significant association between wheat germ interventions and metabolic markers. Sensitive analysis with high-quality RCTs may be worth trying.
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页码：739 / 749
页数：10
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