In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine

被引:0
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作者
Anand Joshi
Brian F. Kiesel
Nupur Chaphekar
Reyna Jones
Jianxia Guo
Charles A. Kunos
Sarah Taylor
Edward Chu
Raman Venkataramanan
Jan H. Beumer
机构
[1] University of Pittsburgh,Department of Pharmaceutical Sciences, School of Pharmacy
[2] UPMC Hillman Cancer Center,Cancer Therapeutics Program
[3] National Cancer Institute,Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis
[4] University of Pittsburgh-Magee Women’s Hospital,Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Medicine
[5] University of Pittsburgh School of Medicine,Division of Hematology
[6] University of Pittsburgh,Oncology, Department of Medicine
来源
关键词
Triapine; Metabolism; Drug–drug interaction; CYP450; Metabolic pathway;
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学科分类号
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页码:633 / 640
页数:7
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