Skeletal myogenesis by human embryonic stem cells

被引:0
作者
Jun Ke Zheng
Yi Wang
Aditi Karandikar
Qian Wang
Hui Gai
Ai Lian Liu
Chao Peng
Hui Zhen Sheng
机构
[1] Center for Developmental Biology,
[2] Xinhua Hospital,undefined
[3] School of Medicine,undefined
[4] Shanghai Jiao Tong University,undefined
[5] Laboratory of Stem Cell Biology,undefined
[6] Institute of Biochemistry and Cell Biology,undefined
[7] Shanghai Institutes of Biological Sciences,undefined
[8] Chinese Academy of Sciences,undefined
来源
Cell Research | 2006年 / 16卷
关键词
Skeletal myogenesis; embryonic stem cell; differentiation;
D O I
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中图分类号
学科分类号
摘要
We have examined the myogenic potential of human embryonic stem (hES) cells in a xeno-transplantation animal model. Here we show that precursors differentiated from hES cells can undergo myogenesis in an adult environment and give rise to a range of cell types in the myogenic lineage. This study provides direct evidences that hES cells can regenerate both muscle and satellite cells in vivo and are another promising cell type for treating muscle degenerative disorders in addition to other myogenic cell types.
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页码:713 / 722
页数:9
相关论文
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