The structure of a T-cell mechanosensor

被引:13
作者
Reinherz, Ellis L. [1 ,2 ]
机构
[1] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
TCR;
D O I
10.1038/d41586-019-02646-w
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
T-cell receptors orchestrate immune-system responses against infection and cancer. A structure of an entire T-cell receptor complex clarifies its assembly and signalling, and sheds light on its dynamic ligand recognition.
引用
收藏
页码:502 / 504
页数:3
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