Cucurbitacin E reduces IL-1β-induced inflammation and cartilage degeneration by inhibiting the PI3K/Akt pathway in osteoarthritic chondrocytes

被引:0
作者
Lin Wang
Hui Xu
Xin Li
Hongwei Chen
Haigang Zhang
Xunpeng Zhu
Zhijie Lin
Shilei Guo
Zhibo Bao
Haicheng Rui
Wei He
Hui Zhang
机构
[1] the First Affiliated Hospital of Anhui Medical University,Department of Orthopaedics
[2] Anhui Medical University,School of Basic Medicine Sciences
[3] Anhui Medical University,undefined
来源
Journal of Translational Medicine | / 21卷
关键词
Osteoarthritis; Cucurbitacin E; Cellular thermal shift assay; Molecular docking; Molecular dynamics simulation; PI3K/Akt; DMM;
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