TRIP13 knockdown inhibits the proliferation, migration, invasion, and promotes apoptosis by suppressing PI3K/AKT signaling pathway in U2OS cells

被引:0
作者
De-Chen Yu
Xiang-Yi Chen
Hai-Yu Zhou
De-Quan Yu
Xiao-Lei Yu
Yi-Cun Hu
Rui-Hao Zhang
Xiao-Bo Zhang
Kun Zhang
Mao-Qiang Lin
Xi-Dan Gao
Tao-Wen Guo
机构
[1] Lanzhou University Second Hospital,Department of Orthopedics
[2] Xigu Branch of the Second Hospital of Lanzhou University,Department of Orthopedics
[3] Air Force Medical University Tangdu Hospital,Department of Radiotherapy
[4] Air Force Medical University Tangdu Hospital,Department of cardiology
来源
Molecular Biology Reports | 2022年 / 49卷
关键词
Osteosarcoma; Thyroid hormone receptor interacting protein 13; PI3K/AKT signaling pathway; Bioinformatics; U2OS;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:3055 / 3064
页数:9
相关论文
共 87 条
  • [1] Carina V(2019)Adjuvant biophysical therapies in osteosarcoma Cancers (Basel) 11 348-50
  • [2] Costa V(2018)Current and future therapeutic approaches for osteosarcoma Expert Rev Anticancer Ther 1 39-532
  • [3] Sartori M(2015)MicroRNAs in osteosarcoma Clin Chim Acta 9 17-2233
  • [4] Harrison DJ(2014)Osteosarcoma treatment - where do we stand? A state of the art review Cancer Treat Rev 4 523-861
  • [5] Geller DS(2020)The conserved AAA-ATPase PCH-2 (TRIP13) regulates spindle checkpoint strength Mol Biol Cell 20 2219-20
  • [6] Gill JD(2019)Insights into a crucial role of TRIP13 in human cancer Comput Struct Biotechnol J 17 854-4410
  • [7] Zhang J(2021)TRIP13 promotes the proliferation and invasion of lung cancer cells via the Wnt signaling pathway and epithelial-mesenchymal transition J Mol Histol 1 11-262
  • [8] Yan YG(2019)Elevated TRIP13 drives cell proliferation and drug resistance in bladder cancer Am J Transl Res 7 4397-1580
  • [9] Wang C(2019)Metascape provides a biologist-oriented resource for the analysis of systems-level datasets Nat Commun 1 1523-132
  • [10] Luetke A(2021)Tau regulates glioblastoma progression, 3D cell organization, growth and migration via the PI3K-AKT axis Cancers (Basel) 22 5818-1078