High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy

Denton CP(2004)Scleroderma – clinical and pathological advances Best Pract Res Clin Rheumatol 18 271-290

Black CM(1995)Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease modifying interventions. The American College of Rheumatology Committee on Design and Outcomes in Clinical Trials in Systemic sclerosis Arthritis Rheum 38 351-360

White B(2000)Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitis Ann Intern Med 132 947-954

Bauer EA(1998)Case–control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis Arthritis Rheum 41 1613-1619

Goldsmith LA(2006)Cyclophosphamide versus placebo in scleroderma lung disease N Engl J Med 354 2655-2666

White B(1996)Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial Br J Rheumatol 35 364-372

Moore WC(2008)The registry of the German network for systemic scleroderma: frequency of disease subsets and patterns of organ involvement Rheumatology (Oxford) 47 1185-1192

Wigley FM(1988)Scleroderma (systemic sclerosis): classification, subsets and pathogenesis J Rheumatol 15 202-205

Xiao HQ(1990)Scleroderma overlap syndrome Rheum Dis Clin North Am 16 185-198

Wise RA(2002)Scleroderma overlap syndromes Curr Opin Rheumatol 14 704-710

Denton CP(2004)Scleroderma – clinical and pathological advances Best Pract Res Clin Rheumatol 18 271-290

Black CM(1995)Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease modifying interventions. The American College of Rheumatology Committee on Design and Outcomes in Clinical Trials in Systemic sclerosis Arthritis Rheum 38 351-360

White B(2000)Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitis Ann Intern Med 132 947-954

Bauer EA(1998)Case–control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis Arthritis Rheum 41 1613-1619

Goldsmith LA(2006)Cyclophosphamide versus placebo in scleroderma lung disease N Engl J Med 354 2655-2666

White B(1996)Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial Br J Rheumatol 35 364-372

Moore WC(2008)The registry of the German network for systemic scleroderma: frequency of disease subsets and patterns of organ involvement Rheumatology (Oxford) 47 1185-1192

Wigley FM(1988)Scleroderma (systemic sclerosis): classification, subsets and pathogenesis J Rheumatol 15 202-205

Xiao HQ(1990)Scleroderma overlap syndrome Rheum Dis Clin North Am 16 185-198

Wise RA(2002)Scleroderma overlap syndromes Curr Opin Rheumatol 14 704-710