Prophylactic inhibition of NF-κB expression in microglia leads to attenuation of hypoxic ischemic injury of the immature brain

被引：0
作者：
Nahla Zaghloul
Dalibor Kurepa
Mohammad Y. Bader
Nadia Nagy
Mohamed N. Ahmed
机构：
[1] University of Arizona,Department of Pediatrics, Division of Neonatology
[2] Feinstein Institute for Medical Research,Department of Pediatrics, Division of Neonatology
来源：
Journal of Neuroinflammation | / 17卷
关键词：
Periventricular leukomalacia; White matter brain injury; Cerebral palsy; Hypoxia ischemia; NF-κB; Microglia; Oligodendroglia; Neuroprotection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Characterization of iron sequestration response in microglia/macrophages in a model of neonatal hypoxic ischemic brain injury.
    Vithayathil, J.
    Jensen, F.
    Talos, D.
    Dunaief, J.
    ANNALS OF NEUROLOGY, 2025, 96 : S144 - S145
  • [22] Is Fos protein expressed by dying striatal neurons after immature hypoxic-ischemic brain injury?
    Oorschot, DE
    Black, MJ
    Rangi, F
    Scarr, E
    EXPERIMENTAL NEUROLOGY, 2000, 161 (01) : 227 - 233
  • [23] Neuroprotection with the proteasome inhibitor MLN519 in focal ischemic brain injury:: Relation to nuclear factor κB (NF-κB), inflammatory gene expression, and leukocyte infiltration
    Williams, AJ
    Dave, JR
    Tortella, FC
    NEUROCHEMISTRY INTERNATIONAL, 2006, 49 (02) : 106 - 112
  • [24] Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury
    Golubinskaya, Veronika
    Vontell, Regina
    Supramaniam, Veena
    Wyatt-Ashmead, Josephine
    Gustafsson, Helena
    Mallard, Carina
    Nilsson, Holger
    FRONTIERS IN PHYSIOLOGY, 2019, 10
  • [25] Attenuation of Blood-Brain Barrier Disruption in Traumatic Brain Injury via Inhibition of NKCC1 Cotransporter: Insights into the NF-κB/NLRP3 Signaling Pathway
    Zhang, Zehan
    Wang, Hui
    Tao, Bingyan
    Shi, Xudong
    Chen, Guilin
    Ma, Hengchao
    Peng, Ruiyun
    Zhang, Jun
    JOURNAL OF NEUROTRAUMA, 2025, : 814 - 831
  • [26] Naloxone attenuates ischemic brain injury in rats through suppressing the NIK/IKKα/NF-κB and neuronal apoptotic pathways
    Xuan Wang
    Zu-jun Sun
    Jun-lu Wu
    Wen-qiang Quan
    Wei-dong Xiao
    Helen Chew
    Cui-min Jiang
    Dong Li
    Acta Pharmacologica Sinica, 2019, 40 : 170 - 179
  • [27] Naloxone attenuates ischemic brain injury in rats through suppressing the NIK/IKKα/NF-κB and neuronal apoptotic pathways
    Wang, Xuan
    Sun, Zu-jun
    Wu, Jun-lu
    Quan, Wen-qiang
    Xiao, Wei-dong
    Chew, Helen
    Jiang, Cui-min
    Li, Dong
    ACTA PHARMACOLOGICA SINICA, 2019, 40 (02) : 170 - 179
  • [28] Inhibition of inflammatory cytokine secretion from mouse microglia cells by DHMEQ, an NF-κB inhibitor
    Takatsuna, H
    Morita, S
    Nagatsu, T
    Sawada, M
    Umezawa, K
    BIOMEDICINE & PHARMACOTHERAPY, 2005, 59 (06) : 318 - 322
  • [29] Electroacupuncture alleviates cerebral ischemia injury by regulating PI3K/AKT/NF-κB signaling in microglia of ischemic stroke rats
    Rao, Rao
    Gan, Lingling
    Zhao, Rui
    Han, Yongsheng
    NEUROREPORT, 2025, 36 (01) : 22 - 30
  • [30] Marine Compound Xyloketal B Reduces Neonatal Hypoxic-Ischemic Brain Injury
    Xiao, Ai-Jiao
    Chen, Wenliang
    Xu, Baofeng
    Liu, Rui
    Turlova, Ekaterina
    Barszczyk, Andrew
    Sun, Christopher Lf
    Liu, Ling
    Deurloo, Marielle
    Wang, Guan-Lei
    Feng, Zhong-Ping
    Sun, Hong-Shuo
    MARINE DRUGS, 2015, 13 (01): : 29 - 47
12345