Renoprotective effects of statins under the conditions of acute renal failure, caused by rhabdomyolysis

被引：0
作者：
Zamorskii I.I. [1 ]
Zeleniuk V.G. [1 ]
机构：
[1] Bukovinian State Medical University, Chernivtsi
来源：
Biophysics | 2014年 / 59卷 / 5期
关键词：
acute renal failure; renoprotection; rhabdomyolysis; statins;
D O I：
10.1134/S0006350914050327
中图分类号：
学科分类号：
摘要：
The experiment on white rats was targeted at the examination of influence of statins (atorvastatin, lovastatin, simvastatin) under the conditions of acute renal failure, caused by rhabdomyolysis. Renoprotective effects of statins were demonstrated by reduction of hyperazotemia and proteinuria and improvement of renal excretory function, which correlated with antioxidant properties of drugs. © 2014, Pleiades Publishing, Inc.
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页码：837 / 840
页数：3
相关论文
共 12 条
  • [1] Vanholder R., Sever M.S., Erek E., Et al., J. Am. Soc. Nephrol., 11, (2000)
  • [2] Bosch X., Poch E., Grau J.M., N. Engl. J. Med., 361, (2009)
  • [3] Tovchiga O.V., Rolik S.M., Shtrigol' S.Y., Ukr. Biofarm. Zh., 2, 13, (2011)
  • [4] Pella D., Rybar R., Mechirova V., Acta. Cardiol. Sin., 21, 4, (2005)
  • [5] Dichtl W., Dulak J., Frick M., Et al., Arterioscler. Thromb. Vasc. Biol., 23, 1, (2003)
  • [6] Stoll L.L., McCormick M.L., Denning G.M., Et al., Drugs Today (Barc)., 40, 12, (2004)
  • [7] Larose E., Ganz P., Semin. Vasc. Med., 4, 4, (2004)
  • [8] Am. J. Cardiol., 96, 5, (2005)
  • [9] Singh A.P., Muthuraman A., Jaggi A.S., Et al., Pharmacol. Reports, 64, (2012)
  • [10] Ryabov S.I., Natochin Y.V., Functional Nephrology, (1997)
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