Acidic ionic liquids: highly efficient catalysts for one-pot four-component synthesis of pyrazolo[1,2-b]phthalazines under solvent-free conditions

被引：0
作者：
Behjat Pouramiri
Reza Ghahramani Far
Mahboobeh Zahedifar
机构：
[1] Shahid Bahonar University of Kerman,Department of Chemistry
[2] Islamic Azad University of Kerman,Department of Chemistry
[3] University of Jiroft,Department of Chemistry, Faculty of Science
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
pyrazolo[1,2-; ]phthalazines; ionic liquid; multicomponent reactions; solvent-free;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of novel pyrazolo[1,2-b]phthalazine-2-carboxylate derivatives has been synthesized via one-pot four-component reaction of aromatic aldehyde, ethyl or methyl acetoacetate, hydrazine hydrate, and phthalic anhydride in the presence of acidic ionic liquids such as 3-methyl-1-sulfo-1H-imidazol-3-ium chloride, 1,3-disulfo-1H-imidazol-3-ium chloride, and triethyl(sulfo)ammonium chloride as the catalyst. This method involves particular advantages such as environmentally benign catalysts, high yields of product, reusability of ionic liquids with high activity, short reaction times, no hazardous solvent, and easy workup.
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页码：1056 / 1060
页数：4
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