Little contribution of GB virus C to the development of primary hepatocellular carcinoma in Japan

被引:0
作者
Yasumasa Nishiyama
Kunihiko Hino
Naoto Sawada
Fumio Tsuda
机构
[1] Second Department of Internal Medicine,
[2] National Defense Medical College,undefined
[3] 3-2 Namiki,undefined
[4] Tokorozawa 359-8513,undefined
[5] Japan,undefined
[6] Department of Medicine and Laboratory Medicine,undefined
[7] St. Marianna University School of Medicine,undefined
[8] Kanagawa,undefined
[9] Japan,undefined
[10] Institute of Immunology,undefined
[11] Tokyo,undefined
[12] Japan,undefined
[13] Department of Medical Sciences,undefined
[14] Toshiba General Hospital,undefined
[15] Tokyo,undefined
[16] Japan,undefined
来源
Journal of Gastroenterology | 1999年 / 34卷
关键词
Key words: hepatitis viruses; GB virus C; hepatitis B virus; hepatitis C viruses; hepatocellular carcinoma;
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摘要
RNA of GB virus C was searched for in sera from 109 patients with primary hepatocellular carcinoma. It was detected in 11 patients (10%), and was more frequent than in 3 of 342 blood donors (0.9%) (P < 0.001). The 11 patients included 4 of 29 patients (14%) with hepatitis B surface antigen and 7 of 74 patients (9%) with antibody to hepatitis C virus. RNA of GB virus C was not detected in any of 4 patients without hepatitis B surface antigen or antibody to hepatitis C virus. These results suggest that GB virus C may contribute little to the development of primary hepatocellular carcinoma in Japan.
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页码:494 / 497
页数:3
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