2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway

被引:0
作者
Zhengjie Chen
Liangyu Zheng
Gang Chen
机构
[1] Zhejiang University,Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine
来源
Cardiovascular Drugs and Therapy | 2023年 / 37卷
关键词
Diabetic cardiomyopathy; 2-Arachidonoylglycerol; Myocardial Fibrosis; TGF-β1;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:647 / 654
页数:7
相关论文
共 80 条
  • [1] Benjamin EJ(2019)Heart disease and stroke statistics-2019 update: a report from the American Heart Association Circulation 139 e56-e528
  • [2] Muntner P(1972)New type of cardiomyopathy associated with diabetic glomerulosclerosis Am J Cardiol 30 595-602
  • [3] Alonso A(2009)Diabetic cardiomyopathy--a distinct disease? Best Pract Res Clin Endocrinol Metab 23 347-360
  • [4] Rubler S(2002)The role of myocardial fibrillar collagen in ventricular remodeling and function J Card Fail 8 S319-S325
  • [5] Dlugash J(2008)Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options Am J Med 121 748-757
  • [6] Yuceoglu YZ(1994)Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms J Mol Cell Cardiol 26 279-292
  • [7] Khavandi K(2017)Targeting TGF-beta mediated SMAD signaling for the prevention of fibrosis Front Pharmacol 8 461-1781
  • [8] Khavandi A(2018)Matrine suppresses cardiac fibrosis by inhibiting the TGFbeta/Smad pathway in experimental diabetic cardiomyopathy Mol Med Rep 17 1775-304
  • [9] Asghar O(2014)Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy Drug Discov Today 19 295-276
  • [10] Janicki JS(2009)Endocannabinoids and the heart J Cardiovasc Pharmacol 53 267-7114