Primary central nervous system lymphoma: essential points in diagnosis and management

被引：0
作者：
Semra Paydas
机构：
[1] Cukurova University,Department of Medical Oncology, Faculty of Medicine
来源：
Medical Oncology | 2017年 / 34卷
关键词：
Primary central nervous system lymphoma; Pathogenesis; Prognosis; Management; Chemotherapy; Radiotherapy;
D O I：
暂无
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学科分类号：
摘要：
Primary central nervous system lymphoma (PCNSL) is an extra-nodal non-Hodgkin lymphoma. PCNSL is defined as lymphoma involving the brain, leptomeninges, eyes, or spinal cord without evidence of lymphoma outside the CNS. Treatment includes induction with chemotherapy and consolidation with whole-brain radiotherapy or high-dose chemotherapy supported by autologous stem cell transplantation. High-dose methotrexate is the most important drug in cases with PCNSL, and this drug will be used in combination with small molecules, BTK inhibitors, new monoclonal antibodies, and checkpoint blockers.
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