African trypanosomiasis: Changing epidemiology and consequences

被引：9

作者：

Chretien J.-P. ^{[1
]}

Smoak B.L. ^{[1
]}

机构：

[1] DoD-GEIS, Division of Preventive Medicine, Walter Reed Army Inst. of Research, Silver Spring, MD 20910

来源：

Current Infectious Disease Reports | 2005年 / 7卷 / 1期

关键词：

Suramin; Pentamidine; Central Nervous System Involvement; Human African Trypanosomiasis; Trypanosomiasis;

D O I：

10.1007/s11908-005-0024-y

中图分类号：

学科分类号：

摘要：

Human African trypanosomiasis has re-emerged as a serious public health threat after near-elimination because of diminished investment in previously successful control programs. The continued, occasional importation of African trypanosomiasis to the United States can be expected as tourists and immigrants travel from high-risk areas. No vaccine or chemoprophylaxis is available for this disease, and travelers to affected areas should be counseled on tsetse fly avoidance. New diagnostic and staging tests are promising but have not replaced the classical method of examining body fluids for trypanosomes. Prompt diagnosis and staging is essential because if untreated, East African and West African sleeping sickness are fatal. Drug regimens are toxic and cumbersome, and short-term prospects for therapeutic advances are limited. Copyright © 2005 by Current Science Inc.

引用

页码：54 / 60

页数：6

共 37 条

[1]

African Trypanosomiasis, WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases, (2000)

[2]

Moore A., Human African trypanosomiasis: A reemerging public health threat, Emerging Infections, pp. 143-157, (2004)

[3]

Magnus E., Vervoort T., Van Meirvenne N., A card-agglutination test with stained trypanosomes (C.A.T.T.) for the serological diagnosis of T.B. gambiense trypanosomiasis, Ann. Soc. Belg. Med. Trop., 58, pp. 169-176, (1978)

[4]

Abel P.M., Kiala G., Loa V., Et al., Retaking sleeping sickness control in Angola, Trop. Med. Int. Health, 9, pp. 141-148, (2004)

[5]

Stanghellini A., Josenando T., The situation of sleeping sickness in Angola: A calamity, Trop. Med. Int. Health, 6, pp. 330-334, (2001)

[6]

Moore A., Richer M., Re-emergence of epidemic sleeping sickness in southern Sudan, Trop. Med. Int. Health, 6, pp. 342-347, (2001)

[7]

Van Nieuwenhove S., Betu-Ku-Mesu V.K., Diabakana P.M., Et al., Sleeping sickness resurgence in the DRC: The past decade, Trop. Med. Int. Health, 6, pp. 335-341, (2001)

[8]

Robays J., Ebeja Kadima A., Lutumba P., Et al., Human African trypanosomiasis amongst urban residents in Kinshasa: A case-control study, Trop. Med. Int. Health, 9, pp. 869-875, (2004)

[9]

Hutchinson O.C., Fevre E.M., Carrington M., Welburn S.C., Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda, Lancet Infect. Dis., 3, pp. 42-45, (2003)

[10]

Waiswa C., Olaho-Mukani W., Katunguka-Rwakishaya E., Domestic animals as reservoirs for sleeping sickness in three endemic foci in south-eastern Uganda, Ann. Trop. Med. Parasitol., 97, pp. 149-155, (2003)

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