Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

被引:0
作者
Yao Wang
Mi Tian
Jiaying Tan
Xu Pei
Chaocheng Lu
Yuewen Xin
Shuixiang Deng
Feng Zhao
Yanqin Gao
Ye Gong
机构
[1] Fudan University,Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science
来源
Journal of Neuroinflammation | / 19卷
关键词
Integrin αVβ5; Intracerebral hemorrhage; Irisin; AMPK; Neuroinflammation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 478 条
  • [1] Keep RF(2012)Intracerebral haemorrhage: mechanisms of injury and therapeutic targets Lancet Neurol 11 720-731
  • [2] Hua Y(2017)The high cost of stroke and stroke cytoprotection research Transl Stroke Res 8 307-317
  • [3] Xi G(2021)Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage Ther Adv Neurol Disord 14 17562864211049208-S150
  • [4] Lapchak PA(2014)Spontaneous intracerebral and intraventricular hemorrhage: advances in minimally invasive surgery and thrombolytic evacuation, and lessons learned in recent trials Neurosurgery 74 S142-102
  • [5] Zhang JH(2018)Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice J Cereb Blood Flow Metab 38 87-46
  • [6] Bautista W(2020)Neuroinflammation after intracerebral hemorrhage and potential therapeutic targets J Stroke 22 29-939
  • [7] Adelson PD(2019)Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage Prog Neurobiol 178 101610-44
  • [8] Bicher N(2020)Recombinant adiponectin peptide ameliorates brain injury following intracerebral hemorrhage by suppressing astrocyte-derived inflammation via the inhibition of Drp1-mediated mitochondrial fission Transl Stroke Res 11 924-8
  • [9] Themistocleous M(2019)NDP-MSH binding melanocortin-1 receptor ameliorates neuroinflammation and BBB disruption through CREB/Nr4a1/NF-κB pathway after intracerebral hemorrhage in mice J Neuroinflammation 16 192-289
  • [10] Tsivgoulis G(2014)Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation Prog Neurobiol 115 25-740