Alkaloids of Aconitum coreanum. X. Curare-Like Activity-Structure Relationship

被引：0

作者：

F. N. Dzhakhangirov

I. A. Bessonova

机构：

[1] Academy of Sciences of the Republic of Uzbekistan,S.Yu. Yunusov Institute of the Chemistry of Plant Substances

来源：

Chemistry of Natural Compounds | 2002年 / 38卷

关键词：

Ranunculaceae; diterpenoid alkaloids; toxicity; curare-like activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The biological activity of 11 alkaloids isolated from Aconitum coreanum was studied. The compounds exhibit myorelaxant activity. Isoatisine and coryphine, which contain oxazolidine rings, are the most active. N-Oxides of 2-isobutyryl-14-hydroxyhetisine and 2-isobutyryl-13-acetyl-14-hydroxyhetisine are least active.

引用

页码：74 / 77

页数：3

共 6 条

[1] Alkaloids of Aconitum coreanum.: X.: Curare-like activity-structure relationship
Dzhakhangirov, FN
Bessonova, IA
CHEMISTRY OF NATURAL COMPOUNDS, 2002, 38 (01) : 74 - 77
[2] Aconitum and Delphinium alkaloids of curare-like activity. QSAR analysis and molecular docking of alkaloids into AChBP
Turabekova, M. A.
Rasulev, B. F.
Dzhakhangirov, F. N.
Leszczynska, D.
Leszczynski, J.
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[3] SOME ASPECTS OF THE RELATIONSHIP BETWEEN CHEMICAL CONSTITUTION AND CURARE-LIKE ACTIVITY
BOVET, D
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1951, 54 (03) : 407 - 437
[4] Structure-Activity Relationship of Insecticidal Steroids. X. Androstane and Pregnane Derivatives
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Zh. N. Kashkan
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[5] Structure-activity relationship of insecticidal steroids. X. Androstane and pregnane derivatives
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Ananich, SK
Kashkan, ZN
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CHEMISTRY OF NATURAL COMPOUNDS, 2002, 38 (06) : 586 - 588
[6] Studies on organophosphorus heterocycles part X. Synthesis of 1,4-diphenyl-1,4,2-diazaphospholidin-5-one-2-oxides and their quantitative structure - Herbicidal activity relationship
He, LN
Cai, F
Chen, RY
Zhou, J
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1997, 130 : 65 - 71

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