Strong alkaline condition is preferable for producing 7,10-dihydroxy-8(E)-hexadecenoic acid from palmitoleic acid by Pseudomonas aeruginosa KNU-2B

被引：0
作者：
Ji-Sun Moon
Yeon-Jung Lee
In-Hwan Kim
Hak-Ryul Kim
机构：
[1] Kyungpook National University,School of Food Science and Biotechnology
[2] Korea University,Department of Public Health Sciences, Graduate School
[3] Kyungpook National University,Institute of Agricultural Science & Technology
来源：
Biotechnology Letters | 2020年 / 42卷
关键词：
Palmitoleic acid; Dihydroxy fatty acid; Alkaline condition; Bioconversion; KNU-2B;
D O I：
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中图分类号：
学科分类号：
摘要：
Microbial bioconversion of a given substrate is considered an efficient and eco-friendly tool for value-added industrial compound generation from natural products. Among natural products, unsaturated fatty acids have been used as substrates to produce various functional hydroxy fatty acids. In this study, we report the production of 7,10-dihydroxy-8(E)-hexadecenoic acid (DHD) from palmitoleic acid by a new strain, Pseudomonas aeruginosa KNU-2B. KNU-2B efficiently produced DHD from palmitoleic acid and required a strong alkaline condition for maximum DHD production. The maximum DHD amount produced under pH 10.0 and 48-h incubation at 27 °C and 150 rpm was 219.5 mg/100 mL culture. Other important nutritional factors were also investigated to obtain optimum DHD production.
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页码：1755 / 1766
页数：11
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