Efficacy of GAD-alum immunotherapy associated with HLA-DR3-DQ2 in recently diagnosed type 1 diabetes

被引:0
|
作者
Ulf Hannelius
Craig A. Beam
Johnny Ludvigsson
机构
[1] Diamyd Medical AB,Department of Biomedical Sciences
[2] Western Michigan University Homer Stryker M.D. School of Medicine,Division of Pediatrics, Department of Biomedical and Clinical Sciences (BKV), Medical Faculty
[3] Crown Princess Victoria Children’s Hospital,undefined
[4] Linköping University,undefined
来源
Diabetologia | 2020年 / 63卷
关键词
Antigen-specific; Autoimmune diabetes; C-peptide; GAD; Glutamic acid decarboxylase; HLA; Immunotherapy; Type 1 diabetes; Vaccine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2177 / 2181
页数:4
相关论文
共 49 条
  • [31] Intralymphatic glutamic acid decarboxylase administration in type 1 diabetes patients induced a distinctive early immune response in patients with DR3DQ2 haplotype
    Puente-Marin, Sara
    Dietrich, Fabricia
    Achenbach, Peter
    Barcenilla, Hugo
    Ludvigsson, Johnny
    Casas, Rosaura
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [32] Next Generation Sequencing Identifies the HLA-DQA1*03:03 Allele in the Type 1 Diabetes Risk-Associated HLA-DQ8 Serotype
    Enczmann, Juergen
    Balz, Vera
    Hoffmann, Maximilian
    Kummer, Sebastian
    Reinauer, Christina
    Doing, Carsten
    Fortsch, Katharina
    Welters, Alena
    Mayatepek, Ertan
    Meissner, Thomas
    Jacobsen, Marc
    Seyfarth, Julia
    GENES, 2021, 12 (12)
  • [33] HLA-DR4-Associated T and B Cell Responses to Specific Determinants on the IA-2 Autoantigen in Type 1 Diabetes
    McLaughlin, Kerry A.
    Gulati, Kavita
    Richardson, Carolyn C.
    Morgan, Diana
    Bodansky, H. Jonathan
    Feltbower, Richard G.
    Christie, Michael R.
    JOURNAL OF IMMUNOLOGY, 2014, 193 (09) : 4448 - 4456
  • [34] TNFa-e microsatellite, HLA-DRB1 and-DQB1 alleles and haplotypes in Brazilian patients presenting recently diagnosed type 1 diabetes mellitus
    Rassi, Diane M.
    Wastowski, Isabela J.
    Simoes, Renata T.
    Rodrigues, Sandra
    Deghaide, Neife N. H. S.
    Mendes-Junior, Celso T.
    Simoes, Aguinaldo L.
    Soares, C. P.
    Passos, Geraldo A. S.
    Donadi, Eduardo A.
    IMMUNOLOGY OF DIABETES IV: PROGRESS IN OUR UNDERSTANDING, 2006, 1079 : 300 - 304
  • [35] HLA DQ2/DQ8 haplotypes and anti-transglutaminase antibodies as celiac disease markers in a pediatric population with type 1 diabetes mellitus
    Oliveira, Diana Rita
    Rebelo, Joana Freitas
    Maximiano, Cristiana
    Gomes, Maria Miguel
    Martins, Vania
    Meireles, Carla
    Antunes, Henedina
    Martins, Sofia
    ARCHIVES OF ENDOCRINOLOGY METABOLISM, 2022, 66 (02):
  • [36] Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07)
    Zhao, Lue Ping
    Papadopoulos, George K.
    Skyler, Jay S.
    Parikh, Hemang M.
    Kwok, William W.
    Bondinas, George P.
    Moustakas, Antonis K.
    Wang, Ruihan
    Pyo, Chul-Woo
    Nelson, Wyatt C.
    Geraghty, Daniel E.
    Lernmark, Ake
    DIABETES CARE, 2024, 47 (09) : 1608 - 1616
  • [37] Frequency of MICA in all babies in southeast Sweden (ABIS) positive for high-risk HLA-DQ associated with type 1 diabetes
    Gupta, M
    Ludvigsson, J
    Sanjeevi, CB
    IMMUNOLOGY OF DIABETES III, 2004, 1037 : 138 - 144
  • [38] Length of gestation and gender are associated with HLA genotypes at risk for Type 1 diabetes (Italian DIABFIN 3)
    Locatelli, M.
    Buzzetti, R.
    Galgani, A.
    Montemari, A. L.
    Khazrai, M.
    Petrone, A.
    Visalli, N.
    Meschi, F.
    Minicucci, L.
    Lorini, R.
    Cristaldi, A.
    Valorani, M. G.
    Bottazzo, G. F.
    Pozzilli, P.
    DIABETIC MEDICINE, 2007, 24 (08) : 916 - 919
  • [39] T cell reactivity to DR*0401-and DQ*0302-binding peptides of the putative autoantigen IA-2 in type 1 diabetes
    Lohmann, T
    Halder, T
    Engler, J
    Morgenthaler, NG
    Khoo-Morgenthaler, UY
    Schröder, S
    Seissler, J
    Scherbaum, WA
    Kalbacher, H
    EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 1999, 107 (03) : 166 - 171
  • [40] Association of interleukin-4, interleukin-13 gene polymorphisms, HLA-DQ and DR genotypes with genetic susceptibility of type-1 Diabetes Mellitus in Kuwaiti children
    Haider, Mohammad Z.
    Al Rushood, Maysoun
    Alsharhan, Hind
    Rasoul, Majedah A.
    Al-Mahdi, Maria
    Al-Kandari, Hessa
    FRONTIERS IN PEDIATRICS, 2023, 11