New variations in human OX40 ligand (CD134L) gene

被引：0

作者：

K Hikami

N Tsuchiya

K Tokunaga

机构：

[1] Graduate School of Medicine,Department of Human Genetics

[2] University of Tokyo,undefined

来源：

Genes & Immunity | 2000年 / 1卷

关键词：

OX40L (CD134L); single nucleotide polymorphism; Japanese; rheumatoid arthritis; systemic lupus erythematosus;

D O I：

暂无

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学科分类号：

摘要：

We found three new variations in the OX40 ligand (OX40L, CD134L) gene and its 5′ upstream region. −921 (G → A) at 5′ upstream region, −19 (C → G) at 5′ untranslated region, and 202+25 (G → T) at intron 2 were identified. −921 (G → A) and 202+25 (G → T) were detected in a substantial proportion of healthy Japanese individuals and were considered to be single nucleotide polymorphisms (SNPs). −19 (C → G) was detected in only one healthy individual. There was no association between these variations and the presence of rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).

引用

页码：521 / 522

页数：1