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NE Normal Univ, Sch Life Sci, Inst Cytol & Genet, Natl Engn Lab Druggable Gene & Prot Screening, Changchun 130024, Peoples R China NE Normal Univ, Sch Life Sci, Inst Cytol & Genet, Natl Engn Lab Druggable Gene & Prot Screening, Changchun 130024, Peoples R China