Application of Fluid–Structure Interaction Methods to Estimate the Mechanics of Rupture in Asian Abdominal Aortic Aneurysms

被引：19

作者：

Canchi T. ^{[1
]}

Saxena A. ^{[1
]}

Ng E. ^{[1
]}

Pwee E.C. ^{[1
]}

Narayanan S. ^{[2
]}

机构：

[1] School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore

[2] Department of General Surgery, Tan Tock Seng Hospital, Singapore

来源：

BioNanoScience | 2018年 / 8卷 / 04期

关键词：

Abdominal aortic aneurysm; Asian patient geometry; Fluid–structure interaction; Patient-specific; Rupture risk;

D O I：

10.1007/s12668-018-0554-z

中图分类号：

学科分类号：

摘要：

Abdominal aortic aneurysms (AAAs) occur because of dilation of the infra-renal aorta to more than 150% of its initial diameter. Progression to rupture is aided by several pathophysiological and biomechanical factors. Surgical intervention is recommended when the aneurysm maximum transverse diameter (DAAA) exceeds 55 mm. A system model that incorporates biomechanical parameters will improve prognosis and establish a relationship between AAA geometry and rupture risk. Two Asian patient-specific AAA geometries were obtained from an IRB-approved vascular database. A biomechanical model based on the fluid–structure interaction (FSI) method was developed for a small aneurysm with DAAA of 35 mm and a large aneurysm with a corresponding diameter of 75 mm. The small aneurysm (patient 1) developed a maximum principal stress (PS1) of 3.16e5 Pa and the large aneurysm (patient 2) developed a PS1 of 2.32e5 Pa. Maximum deformation of arterial wall was 0.0020 m and 0.0022 m for patients 1 and 2 respectively. Location of maximum integral wall shear stress (WSS) (fluid) was different from that of PS1. Induced WSS was also higher in patient 1 (18.74 Pa vs 12.88 Pa). An FSI model incorporating the effect of both the structural and fluid domains aids in better understanding of the mechanics of AAA rupture. Patient 1, having a lower DAAA than patient 2, developed a larger PS1 and WSS. It may be concluded that DAAA may not be the sole determinant of AAA rupture risk. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.

引用

页码：1035 / 1044

页数：9

共 34 条

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