Influence of inhomogeneities in muscle tissue on single-fibre action potentials: a model study

被引：0
作者：
W. L. C. Rutten
B. K. van Veen
S. H. Stroeve
H. B. K. Boom
W. Wallinga
机构：
[1] University of Twente,Institute for Biomedical Technology, Department of Electrical Engineering, Biomedical Engineering Division
[2] Medtronic Company,Mechanical Engineering Faculty
[3] Delft University of Technology,undefined
来源：
Medical and Biological Engineering and Computing | 1997年 / 35卷
关键词：
Blood vessel; Boundary effects; Connective tissue; Finite-element modelling; Single-muscle fibre action potential; Volume conduction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The influence of changes in electrical conductivity, due to the muscle boundary, layers and compartments of intramuscular connective tissue and blood vessels, on computed single-muscle fibre action potentials (SFAPs) in rat hindleg muscle is calculated. The position of the active fibre is varied throughout the muscle. For fibres close to the muscle boundary, peak-to-peak voltages of SFAPs increase by up to a factor of 3 compared with the unbounded situation. For inner fibres, the presence of nearby connective tissue compartments causes an increase of up to 40%. A blood vessel in the neighbourhood of the active fibre leads to a decrease of at most 20%, for recording sites between the active fibre and the blood vessel. For recording sites beyond the blood vessel, peak-to-peak voltages increase by up to 20%.
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页码：91 / 95
页数：4
相关论文
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