Multiplex PCR performed of bronchoalveolar lavage fluid increases pathogen identification rate in critically ill patients with pneumonia: a pilot study

被引:0
作者
Jean-Luc Baudel
Jacques Tankovic
Redouane Dahoumane
Fabrice Carrat
Arnaud Galbois
Hafid Ait-Oufella
Georges Offenstadt
Bertrand Guidet
Eric Maury
机构
[1] Service de Réanimation Médicale,1Assistance Publique
[2] Service de Microbiologie, Hôpitaux de Paris (AP
[3] Inserm,HP), Hôpital Saint
[4] UMR 707,Antoine
[5] UPMC - Université Paris 06,AP
来源
Annals of Intensive Care | / 4卷
关键词
Multiplex PCR; SeptiFast®; Bronchoalveolar lavage; Antibiotic therapy; Prior antibiotic treatment; Community-acquired pneumonia; Hospital-acquired pneumonia; Ventilator-acquired pneumonia;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 303 条
  • [1] Bodmann KF(2005)Current guidelines for the treatment of severe pneumonia and sepsis Chemotherapy 51 227-233
  • [2] Zilberberg MD(2008)Antimicrobial therapy escalation and hospital mortality among patients with health-care-associated pneumonia: a single-center experience Chest 134 963-968
  • [3] Shorr AF(2001)Impact of appropriateness of initial antibiotic therapy on the outcome of ventilator-associated pneumonia Intensive Care Med 27 355-362
  • [4] Micek ST(2000)Value of gram stain examination of lower respiratory tract secretions for early diagnosis of nosocomial pneumonia Am J Respir Crit Care Med 162 1731-1737
  • [5] Mody SH(1991)Diagnosis of nosocomial pneumonia in mechanically ventilated patients. Comparison of a plugged telescoping catheter with the protected specimen brush Am Rev Respir Dis 143 1055-1061
  • [6] Kollef MH(2010)Diagnostic techniques and procedures for establishing the microbial etiology of ventilator-associated pneumonia for clinical trials: the pros for quantitative cultures Clin Infect Dis 51 S88-S92
  • [7] Dupont H(2007)Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults Clin Infect Dis 44 S27-S72
  • [8] Mentec H(2010)Automated extraction improves multiplex molecular detection of infection in septic patients PLoS One 5 e13387-604
  • [9] Sollet JP(2008)Molecular diagnosis of sepsis in neutropenic patients with haematological malignancies J Med Microbiol 57 601-1492
  • [10] Bleichner G(2008)Multiplex polymerase chain reaction detection enhancement of bacteremia and fungemia Crit Care Med 36 1487-351