Sporadic primary malignant intracerebral nerve sheath tumors: case report and literature review

被引：0
作者：
Zachary Rollins Barnard
Pankaj Kumar Agarwalla
Deva Sanjeeva Jeyaretna
Christopher James Farrell
Elizabeth Robins Gerstner
Di Tian
William Thomas Curry
机构：
[1] Massachusetts General Hospital,Department of Surgery (Neurosurgery)
[2] Harvard Medical School,Department of Surgery (Neurosurgery)
[3] Massachusetts General Hospital,Stephen E. and Catherine Pappas Center for Neuro
[4] Massachusetts General Hospital Cancer Center,Oncology
[5] Massachusetts General Hospital,Department of Neurology
[6] Harvard Medical School,Department of Pathology
[7] Massachusetts General Hospital,undefined
[8] Harvard Medical School,undefined
来源：
Journal of Neuro-Oncology | 2011年 / 104卷
关键词：
MINST; MPNST; Schwannoma; Spindle cell neoplasm;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report the case of a seventy-five year old woman with a sporadic primary malignant intracerebral nerve sheath tumor (MINST). These tumors fall within the spectrum of malignant peripheral nerve sheath tumors (MPNST) but confirming the diagnosis of a MINST can be difficult due to its rarity and unusual intraparenchymal location. Radiographically, MINST’s mimic malignant glioma and should be considered in the differential diagnosis of enhancing cerebral lesions. In this report, we present a comprehensive panel of histological, immunohistochemical, ultrastructural, and genetic considerations that may be used to diagnosis MINST based on their similarities to MPNSTs and brain parenchyma location.
引用
收藏
页码：605 / 610
页数：5
相关论文
共 83 条
[1]  
Stefanko SZ(1986)Intracerebral malignant schwannoma Acta Neuropathol 71 321-325
[2]  
Vuzevski VD(1993)Malignant schwannoma of the cerebellum: case report Surg Neurol 39 128-132
[3]  
Maas AI(1998)Malignant intracerebral nerve sheath tumor: a case report and review of the literature Cancer 82 545-552
[4]  
van Vroonhoven CC(2000)Malignant intracerebral nerve sheath tumor with intratumoral calcification. Case report J Neurosurg 92 338-341
[5]  
Singh RV(2004)Malignant nerve sheath tumor of the right cerebral peduncle: case report Neurosurgery 54 500-503
[6]  
Suys S(2008)Intrapontine malignant nerve sheath tumor: MRI and MRS features Acta Neurol Belg 108 67-71
[7]  
Campbell DA(1984)Immunocytochemistry of recurring intracerebral nerve sheath tumor J Neuropathol Exp Neurol 43 1-620
[8]  
Broome JC(2007)Malignant peripheral nerve sheath tumors Neurosurg Focus 22 12-444
[9]  
Sharma S(1989)Malignant peripheral nerve sheath tumor (MPNST) showing perineurial cell differentiation Am J Surg Pathol 13 613-3552
[10]  
Abbott RI(1985)Malignant peripheral nerve-sheath tumors (malignant schwannomas). An immunohistochemical study of 29 cases Am J Surg Pathol 9 434-2021
123456789