Primary squamous cell carcinoma of the pancreas: A case report and review of the literature

被引：0

作者：

Kodavatiganti R. ^{[1
]}

Campbell F. ^{[1
,2
]}

Hashmi A. ^{[1
]}

Gollins S.W. ^{[1
]}

机构：

[1] North Wales Cancer Treatment Centre, Glan Clwyd Hospital, Denbighshire, LL18 5UJ, Sarn Lane

[2] Department of Histopathology, Royal Liverpool and Broadgreen University, Hospitals NHS Trust, Liverpool, L7 8XP, Prescot street

来源：

Journal of Medical Case Reports | / 6卷 / 1期

关键词：

Squamous Cell Carcinoma; Adenosquamous Carcinoma; Esophageal Squamous Cell Cancer; Multiple Liver Metastasis; Lung Squamous Cell Carcinoma;

D O I：

10.1186/1752-1947-6-295

中图分类号：

学科分类号：

摘要：

Introduction: Primary squamous cell carcinoma of the pancreas is a rare tumor with poor prognosis and is found in the literature only as case reports. The optimal management course remains poorly defined. We present a case of primary basaloid squamous cell carcinoma of the pancreas metastatic to the liver, which was treated with surgery and systemic chemotherapy. Our patient survived for 15 months: the longest survival reported in the literature to date. Case presentation: A 70-year-old Caucasian man presented to hospital with a three-month history of weight loss, pruritus and icterus. Imaging studies confirmed the presence of an operable mass lesion in the head of the pancreas. Following a pancreaticoduodenectomy, histology results led us to make a diagnosis of squamous cell carcinoma. Postoperative restaging showed multiple metastases in the liver. He underwent palliative systemic chemotherapy with cisplatin and 5-fluorouracil achieving partial response and an excellent quality of life. He then went on to start second-line chemotherapy, but unfortunately died of sepsis soon thereafter. Conclusions: This case report emphasizes that achievement of a worthwhile objective and symptomatic palliative response is possible using platinum-based chemotherapy in squamous cell carcinoma of the pancreas. © 2012 Kodavatiganti et al.; licensee BioMed Central Ltd.

引用

共 13 条

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