Gastrointestinal stromal tumour presenting with severe bleeding: a review of the molecular biology

被引：0
作者：
E. Towu
M. Stanton
机构：
[1] Lewisham University Hospital NHS Trust,Department of Paediatric Surgery
[2] Southampton University NHS Trust,Southampton General Hospital
来源：
Pediatric Surgery International | 2006年 / 22卷
关键词：
GIST; Gastrointestinal bleed;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gastrointestinal stromal tumours (GIST) are rare in children. A 7-year-old boy presented acutely with a severe upper gastrointestinal bleed and was found following angiography to have such a tumour in the duodenum, which was resected at laparotomy. The presence of CD 117 positive immunostaining was a confirmatory diagnostic marker. The prognosis and underlying molecular biology of the tumour is discussed. Understanding of the molecular pathogenesis has given rise to promising new therapies.
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页码：462 / 464
页数：2
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