Aptamer-conjugated nanomaterials for specific cancer cell recognition and targeted cancer therapy

被引：0
作者：
Qiaoling Liu
Chen Jin
Yanyue Wang
Xiaohong Fang
Xiaobing Zhang
Zhuo Chen
Weihong Tan
机构：
[1] Molecular Science and Biomedicine Laboratory,Departments of Chemistry
[2] State Key Laboratory of Chemo/Bio-Sensing and Chemometrics,undefined
[3] College of Biology,undefined
[4] College of Chemistry and Chemical Engineering,undefined
[5] Collaborative Innovation Center for Chemistry and Molecular Medicine,undefined
[6] Hunan University,undefined
[7] Beijing National Laboratory for Molecular Sciences,undefined
[8] Institute of Chemistry,undefined
[9] Chinese Academy of Sciences,undefined
[10] Physiology and Functional Genomics,undefined
[11] Molecular Genetics and Microbiology,undefined
[12] and Pathology and Laboratory Medicine,undefined
[13] Shands Cancer Center,undefined
[14] Center for Research at the Bio/Nano Interface,undefined
[15] University of Florida,undefined
来源：
NPG Asia Materials | 2014年 / 6卷
关键词：
aptamer; cancer therapy; cell recognition; nanomaterials;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Based on their unique advantages, increasing interest has been shown in the use of aptamers as target ligands for specific cancer cell recognition and targeted cancer therapy. Recently, the development of aptamer-conjugated nanomaterials has offered new therapeutic opportunities for cancer treatment with better efficacy and lower toxicity. We highlight some of the promising classes of aptamer-conjugated nanomaterials for the specific recognition of cancer cells and targeted cancer therapy. Recent developments in the use of novel strategies that enable sensitive and selective cancer cell recognition are introduced. In addition to targeted drug delivery for chemotherapy, we also review how aptamer-conjugated nanomaterials are being incorporated into emerging technologies with significant improvement in efficiency and selectivity in cancer treatment.
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页码：e95 / e95
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