Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis

[1] Akino T(2009)Cytogenetic abnormalities of tumour-associated endothelial cells in human malignant tumors Am J Pathol 175 2657-2667

[2] Hida K(2012)Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment Am J Pathol 180 1283-1293

[3] Hida Y(2006)Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors Cancer Res 66 2173-2180

[4] Tsuchiya K(2013)Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis Cancer Res 73 583-594

[5] Freedman D(2011)Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane Blood 118 3979-3989

[6] Muraki C(2009)The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells PLoS One 4 e5620-1161

[7] Ohga N(2003)Altered angiogenesis and survival in human tumor-derived endothelial cells FASEB J 17 1159-3166

[8] Matsuda K(2010)High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function Diabetes 59 3159-9165

[9] Akiyama K(1995)Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion Proc Natl Acad Sci USA 92 9161-6309

[10] Harabayashi T(2008)Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer Clin Cancer Res 14 6302-1757

[1] Akino T(2009)Cytogenetic abnormalities of tumour-associated endothelial cells in human malignant tumors Am J Pathol 175 2657-2667

[2] Hida K(2012)Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment Am J Pathol 180 1283-1293

[3] Hida Y(2006)Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors Cancer Res 66 2173-2180

[4] Tsuchiya K(2013)Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis Cancer Res 73 583-594

[5] Freedman D(2011)Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane Blood 118 3979-3989

[6] Muraki C(2009)The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells PLoS One 4 e5620-1161

[7] Ohga N(2003)Altered angiogenesis and survival in human tumor-derived endothelial cells FASEB J 17 1159-3166

[8] Matsuda K(2010)High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function Diabetes 59 3159-9165

[9] Akiyama K(1995)Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion Proc Natl Acad Sci USA 92 9161-6309

[10] Harabayashi T(2008)Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer Clin Cancer Res 14 6302-1757